The suspect was arrested on suspicion of attempted murder, dangerous driving, and driving while unfit through drugs.
Officers believe the man bypassed roadblocks by tailing an ambulance responding to a separate heart attack emergency, with no prior intelligence indicating such an incident.
Eleven people injured in the collision remain in a local medical facility and are reported to be in stable condition.
The investigation is ongoing, and the suspect remains in Police Custody as enquiries continue.
The public can contact Merseyside Police via @MerPolCC on Social Media or by calling 101, quoting Log Number 784.
Alternatively, information can be shared anonymously through CrimeStoppers at 0800 555 111.